Clinical Pathology
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The Clinical Pathology Department conducts research that contributes to intervention strategies and safeguards of public health in Ghana. In view of this the Department carries out research into plant medicine development, drug interactions and regulation, bio-monitoring and prevention of poisoning from environmental toxicants (e.g. mycotoxins specifically aflatoxins and toxic heavy metals). The Department also provides specialized laboratory services in support of public health programmes.
Key Research Area of HOD
- Toxicology/Pharmacology
- Drug development (Drug-drug/ herb-drug/ food-drug interactions and drug metabolizing enzymes)
- Heavy metal studies
Facilities
- Spectrophotometer
- High Performance Liquid Chromatography (HPLC) instrument
- Freeze dryer
- Biosafety Cabinet
- Lumex Mercury analyzer
Projects
Mycotoxin studies
i. Evaluation of palatability and acceptance of NovaSil- treated foods Investigators
ii. Modulation of rat liver microsomal protein-mediated aflatoxin biotransformation by Ghanaian vegetables
iii. Determination of fumonisins in weanimix
Drug Development
i. Chemicaland biological fingerprinting of Ghanaian medicinal plants
ii. Studies on Anti-viral and Anti-Parasitic Compounds from Selected Ghanaian Medicinal Plants: Toxicity of medicinal plants
Drug Interactions
- Survey on the prevalence of co-use of plant and orthodox medicines in the Ga East District of Ghana.
- Cytochrome P450-mediated drug-drug and herb-drug interaction studies on drugs and herbal preparations used to treat malarial, tuberculosis and HIV